TY - JOUR TI - 胰腺实性假肿瘤相关以高架DHEA和睾酮VL - 2019 PY - 2019 DA - 2019年3月28日DO - 10.1155 /八百一十二万八千三百七十六分之二千〇十九UR - https://doi.org/10.1155/2019/8128376AB - 胰腺实性假乳头状瘤(SPN)是极为罕见的上皮性肿瘤具有低度恶性潜能。他们只占1-2%的胰腺癌病变。这些群众往往被忽视,当他们成为有症状往往是由于对邻近结构的质量效果。我们在一个健康的34岁的女性谁被发现有月经不规则的评估过程中提高脱氢表雄酮和睾酮水平遇到了一个不寻常的演示文稿。随后的腹部成像显示,是关于为胰腺肿瘤具有增强2.7厘米胰尾部质量。病人接受超声波内窥镜证实低回声的存在,2.3×1.7厘米质量在胰尾。一个完整的接口被看见的质量和相邻结构之间,这表明不存在局部浸润的。进行细针穿刺活检及细胞学检查与SPN一致。病人后来根治性胰体尾切除,她的月经随后正常化。 SPN are generally inactive on laboratory screening modalities (i.e., AFP, CEA, CA 19-9, and CA 125) and our patient showed no evidence of pancreatic insufficiency, pancreatic parenchymal injury, abnormal liver function, or cholestasis. Similarly to our patient, most SPN are asymptomatic. One retrospective study (spanning 15 years) reported vague abdominal pain in ~70% of patients, on initial presentation. Symptoms of tumor mass effect were the second most common. To our knowledge, this is the first reported presentation of elevated DHEA and testosterone levels associated with a solid pseudopapillary tumor in the absence of an underlying adrenal lesion or dysfunction. Despite extensive workup, no alternate etiology or correlatable medical condition could be elucidated for our patient’s hormonal dysregulation. We, therefore, recommend further review and investigation into this potential correlative relationship in an effort to guide the future diagnosis and management of this unusual neoplasm. JF - Case Reports in Gastrointestinal Medicine SN - 2090-6528 PB - Hindawi SP - 8128376 KW - A2 - Leitman, I. Michael AU - Estifan, Elias AU - Cavanagh, Yana AU - Kapoor, Ashima AU - Grossman, Matthew ER -