TY -的A2 -阿马拉尔·门德斯,瑞盟-穆萨维,Eya盟——Oueslati Yassine盟——Oualha拉弥亚盟——Denguezli Mohamed AU - Sriha Badreddine盟——Douki Nabiha PY - 2021 DA - 2021/10/25 TI -同时口服和脐位置作为第一寻常天疱疮SP - 7792360六世的迹象- 2021 AB -的寻常天疱疮(PV)在自身免疫性大疱的疾病(AIBD)。这是一个获得慢性自身免疫性水疱性疾病,免疫球蛋白抗体目标desmosomal蛋白质生产上皮内黏膜与皮肤的水泡。临床医生的诊断通常是具有挑战性的。它需要结合三个主要特点:临床、组织病理学、免疫。临床、口腔疾病的病变是第一个表现在50 - 90%的患者普遍影响口腔黏膜的水泡。在皮肤上,病变特点是弛缓性水泡迅速进展到侵蚀和地壳的形成。脐病变的临床表现PV是奇特的,很少报道,他们尚未完全阐明。天疱疮患者脐地区参与评估在有限的研究中总计10个病人。这种本地化可能有价值的提示宽松诊断临床水平的患者口腔粘膜水泡。牙医必须熟悉光伏的临床表现作出早期诊断和早期治疗开始决定了疾病的预后。 To the best of the authors’ knowledge, the coexistence of these lesions with the oral lesions as a first sign of PV in the absence of skin involvement was reported in only one case of pemphigus vegetans (PVe). In this paper, we describe an observation of a female patient that was diagnosed with PV that begun with simultaneous oral and umbilical locations which coexisted for a period of 4 months before the appearance of other cutaneous lesions. We highlight the role of dentists, by being familiar with the clinical manifestations of PV, to make an early diagnosis to start an early treatment which determines the prognosis of the disease and to follow closely the evolution of lesions to change treatment if required. We also discuss the clinical, histological, and immunological features of the disease that enabled the differential diagnosis as well as the appropriate therapeutic management. SN - 2090-6447 UR - https://doi.org/10.1155/2021/7792360 DO - 10.1155/2021/7792360 JF - Case Reports in Dentistry PB - Hindawi KW - ER -