TY -的A2 Imig约翰。d . AU - Gallu Mariacarla AU -马伦,会非盟- Legramante,雅格布玛丽亚AU - De洛伦佐Antonino AU - Di丹尼尔·尼古拉AU - Noce安娜莉莎PY - 2020 DA - 2020/06/27 TI -女性性血栓栓塞风险因素的时代Nonvitamin K拮抗剂口服抗凝血剂SP - 1743927六世- 2020 AB -性别差异已经证实心血管疾病(简历)。这些差异也可以对简历疗法的效果的影响。女性性被认为是一个独立的预测血栓栓塞的风险,特别是老年患者。中风是由于大多数心房纤颤(房颤)。女性受到AF中风的风险比男性更高。新型口服抗凝剂的引入(NOACs)长期抗凝完全改变了患者的抗凝治疗方法和后续非瓣膜性房颤的影响(NVAF)。CHA2DS2-VASc中风风险评分使用在当前国际准则属性1点“女性”。除此之外,没有表示对房颤抗凝女性病人没有其他风险因素。有趣的是,似乎NOACs正常男性和女性之间的差异在安全性和有效性方面,而残余更高的中风风险和系统性栓塞坚持女性用维生素K拮抗剂治疗房颤抗凝血剂VKA治疗范围的最佳时间。基于CHA2DS2-VASc得分,NOACs代表NVAF患者的首选。 Moreover, complete evaluation of apparently lower risk factor along with concomitant clinical conditions in AF patients appears mandatory, particularly for female patients, in order to achieve the most appropriate anticoagulant treatment, either in male or in female patients. The present review was performed to review sex differences in AF-related thromboembolic risk reported in the literature and possibly highlight current knowledge gaps in prevention and management that need further research. SN - 1755-5914 UR - https://doi.org/10.1155/2020/1743927 DO - 10.1155/2020/1743927 JF - Cardiovascular Therapeutics PB - Hindawi KW - ER -