TY - JOUR A2 - 秦，胡AU - 文，兰盟 - 王，苏夏AU - 刘，雷盟 - 陈，林AU - 耿佳盟 - 旷，雷盟 - 钱，钢针AU - 苏，俊杰AU -陈，康宁AU - 周，振华PY - 2018 DA - 2018年9月12日TI - 长期疗效和安全性颈的动脉支架术的老年群体：一个单中心的中国SP研究 - 4707104 VL - 2018 AB -相比于颈动脉内膜切除，颈动脉支架置入术（CAS）据报道，在老年患者围手术期的高风险相关联。为了验证CAS与老年患者血栓保护的长期安全性和有效性，我们回顾病人的医疗记录，在一所大学医院的神经内科在中国部2003年1月和2010年3月间治疗颈动脉狭窄。We included patients with symptomatic, moderate, or severe carotid stenosis of atherosclerotic etiology (other etiologies were excluded), with a disability score ≤ 3 on the modified Rankin Scale, and who received CAS instead of carotid endarterectomy. The clinical endpoints studied were stroke recurrence and all-cause death. The 84 patients included in this study (median follow-up, 8.08 years) were stratified according to age at surgery (<70 vs. ≥70 years), and no significant between-group difference was found regarding baseline characteristics. Of the 14 patients (16.67%) who experienced a defined clinical endpoint, 4 (7.14%) were aged <70 years and 10 (35.71%) were aged ≥70 years ( P = 0.002 ）。Overall mortality was 14.29% (12/84), with 3 (5.36%) and 9 (32.14%) deaths among patients aged <70 and ≥ 70 years, respectively ( P = 0.002 ）。心脏疾病和癌症占死亡人数最多。The two groups did not differ regarding stroke recurrence, disability score, or rate of in-stent restenosis (blockage ≥ 50%), but patients aged ≥70 years had a higher risk of mortality (odds ratio, 8.3684; 95% confidence interval, 2.048–34.202; P = 0.003 ），以及年龄死亡的独立危险因素（比值比，20.054; 95％置信区间，3.094-129.987， P = 0.002 ）。在老年患者在中国西南地区，CAS可以有效防止卒中复发而不增加中风有关的死亡危险，但全因死亡的风险较高，随着年龄的增长作为一个独立的危险因素。仔细选择患者是在症状性颈动脉狭窄的治疗至关重要。SN - 0953-4180 UR - https://doi.org/10.1155/2018/4707104 DO - 10.1155 /四百七十○万七千一百〇四分之二千〇一十八JF - 行为神经学PB - Hindawi出版KW - ER -