ty -jour a2 -trojano,luigi au -kovács,mártonau -makkos,attila au -weintraut,rita au -karádi,kázmérau -józsefau -józsefau -kovács,norbert py -2017 -2017 da -2017 da -da -da -norbert au -kovácsPrevalence of Anxiety among Hungarian Subjects with Parkinson’s Disease SP - 1470149 VL - 2017 AB - Although anxiety is one of the most frequent symptoms of Parkinson’s disease (PD), only a few clinical tools can efficiently and reliably detect its presence. The aim of the present study was to validate the Hungarian patient-rated version of Parkinson Anxiety Scale (PAS). A total of 190 PD patients were enrolled into the clinimetric validation phase of the study and another 590 participated in the cross-sectional screening phase. The presence of anxiety disorder was diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders criteria. The cutoff value for PAS which best discriminated the presence of anxiety from the absence was 12.5 points (sensitivity of 88.6%, specificity of 79.9). The area under the curve was 0.847 whereas the ROC analysis yielded the statistical significance level (
p
<
0.001
)。轻度(Hoehn和Yahr阶段,HYS 1和2),中度(HYS 3)和严重(HYS 4和5)疾病阶段的最佳阈值分别为10.5、12.5和13.5分。基于总体阈值焦虑发生在35.8%的患者中(持续性焦虑:29.2%,情节焦虑:20.7%和回避焦虑症:16.8%)。我们证明了PAS是评估焦虑的有效,高度可靠且敏感的工具。SN -0953-4180 UR -https://doi.org/10.1155/2017/1470149 DO -10.1155/2017/2017/1470149 JF-行为神经病学PB -Hindawi KW -er -er-