y - JOUR A2 - Morrison Trudy AU - Essa, Sahar AU - Owayed, Abdullah AU - Altawalah, Haya AU - Khadadah, Mousa AU - Behbehani, Nasser AU - Al-Nakib，Widad PY - 2015 DA - 2015/04/23 TI -混合病毒感染住院患者呼吸道感染传播在科威特SP - 714062六世- 2015 AB -本研究的目的是确定病毒混合检测的频率在住院患者呼吸道感染和病毒之间的关系进行评估mixed detection and clinical severity. Hospitalized patients with respiratory tract infections (RTI) were investigated for 15 respiratory viruses by using sensitive molecular techniques. In total, 850 hospitalized patients aged between 3 days and 80 years were screened from September 2010 to April 2014. Among the 351 (47.8%) patients diagnosed with viral infections, viral mixed detection was identified in 49 patients (14%), with human rhinovirus (HRV) being the most common virus associated with viral mixed detection (7.1%), followed by adenovirus (AdV) (4%) and human coronavirus-OC43 (HCoV-OC43) (3.7%). The highest combination of viral mixed detection was identified with HRV and AdV (2%), followed by HRV and HCoV-OC43 (1.4%). Pneumonia and bronchiolitis were the most frequent reason for hospitalization with viral mixed detection (9.1%). There were statistical significance differences between mixed and single detection in patients diagnosed with bronchiolitis ( P ＝ 0．002 )及肺炎( P ＝ 0.019 ）.我们的发现可能表明，与单次检测相比，呼吸道病毒混合检测与发生更严重的LRTI(如毛细支气管炎和肺炎)的可能性存在显著相关性。SN - 1687-8639 UR - https://doi.org/10.1155/2015/714062 DO - 10.1155/2015/714062 JF - Advances in Virology PB - Hindawi Publishing Corporation KW - ER -