ty -jour a2 -chang,in ho au -ho au -venyo,Anthony Kodzo -Grey PY -2015 DA- 2015/11/11/12 TI-关于前列腺腺初级平滑肌肉瘤的评论,前列腺腺SP -485786 AB- 2015 AB-原理-2015 AB -2015 AB-前列腺(PLSOP)的平滑肌肉瘤很少见,到目前为止,少于200例。PLSOPS存在较低的尿路症状,血尿和会周围的疼痛;可以通过放射疗法和 /或激素治疗的先前治疗前列腺腺癌治疗的病史也可能与前列腺腺癌有关。可能会折磨儿童和成年男性。检查可能显示良性的前列腺肿大和质量增加。PLSOP可以通过在前列腺标本中纺锤形癌细胞的组织学检查发现来诊断。免疫组织化学染色倾向于波形蛋白,CD44,平滑肌肌动蛋白和钙蛋白染色呈阳性,而脱氨蛋白呈阳性,有时对角蛋白呈阳性。它们对PSA,S-100,CD34,CD117和细胞角蛋白造成负面影响。前列腺原发性平滑肌肉瘤的细胞遗传学研究可能显示涉及染色体2、3、9、11和19的克隆染色体重排。总体而言,预后很差。 Surgery with or without chemotherapy would appear to be the mainstay of treatment for PLSOPs that are operable, but generally there is no consensus opinion on the best therapeutic approach. Most cases of PLSOPs are diagnosed in an advanced stage of the disease. A global multicenter trial is required to find therapies that would improve the prognosis. SN - 1687-6369 UR - https://doi.org/10.1155/2015/485786 DO - 10.1155/2015/485786 JF - Advances in Urology PB - Hindawi Publishing Corporation KW - ER -