TY - JOUR A2 - Maponga, Charles Chiedza AU - Memiah, Peter AU - Mbuthia, Wangeci AU - Kiiru, Grace AU - Agbor, Solomon AU - Odhiambo, Francesca AU - Ojoo, Sylvia AU - Biadgilign, Sibhatu PY - 2012 DA - 2012/04/04 TI - Prevalence and Risk Factors Associated with Precancerous Cervical Cancer Lesions among HIV-Infected Women in Resource-Limited Settings SP - 953743 VL - 2012 AB - Objective. To assess the prevalence and identified associated risk factors for precancerous cervical cancer lesions among HIV-infected women in resource-limited settings in Kenya. Methods. HIV-infected women attending the ART clinic at the Nazareth Hospital ART clinic between June 2009 and September 2010. Multivariate logistic regression model with odds ratios and 95% confidence intervals (CI) were estimated after controlling for important covariates. Result. A total of 715 women were screened for cervical cancer. The median age of the participants was 40 years (range 18–69 years). The prevalence of precancerous lesions (CINI, CINII, CIN III, ICC) was 191 (26.7%). After controlling for other variables in logistic regression analysis, cervical precancerous lesions were associated with not being on ART therapy; whereby non-ART were 2.21 times more likely to have precancerous lesions than ART patients [ ( aOR ) = 2.21 , 95% CI (1.28–3.83)]. Conclusion. The prevalence of precancerous cervical lesions was lower than other similar settings. It is recommended that cancer screening of HIV-infected women should be an established practice. Availability and accessibility of these services can be done through their integration into HIV. Prompt initiation of HAART through an early enrollment into care has an impact on reducing the prevalence and progression of cervical precancerous lesions. SN - 2090-1240 UR - https://doi.org/10.1155/2012/953743 DO - 10.1155/2012/953743 JF - AIDS Research and Treatment PB - Hindawi Publishing Corporation KW - ER -