ty -jour a2 -pace，Betty S. au -tshilolo，L。au -summa，V。au -au -gregorj，C.Au -kinsiama -kinsiama，C.Au -bazeboso -bazeboso，J.A.Au -avvisati，Avvisati，G.Au -labie，d。。PY - 2012 DA - 2012/07/05 TI - Foetal Haemoglobin, Erythrocytes Containing Foetal Haemoglobin, and Hematological Features in Congolese Patients with Sickle Cell Anaemia SP - 105349 VL - 2012 AB - High HbF levels and F cells are correlated with reduced morbidity and mortality in sickle cell disease (SCD). This paper was designed to determine the HbF and F cells levels in Congolese sickle cell anemia (SCA) patients in order to determine their impact on the expression of SCD. 人口和方法。使用标准HPLC方法测量了89名SCA患者（平均年龄11.4岁）的HBF水平。F细胞定量是在第二组SCA患者中进行的（ n = 42 ，平均年龄8.9岁），并与对照组进行比较（ n = 47 ，平均5岁）。F细胞通过细胞荧光测量系统（MoAb-HBF-FITC；切断为0.5％）进行定量。 结果。HBF的平均值为7.2％  ±  5.0 with heterogeneous distribution, most patients (76%) having HbF < 8%. Mean values of F-cells in SCA patients and control group were 5.4%  ±  7.6 (median: 2.19% ; range 0,0–30,3%) and 0.5%  ±  1.6 (median 0.0, range 0–5.18), respectively. SCA patients with F cells >4.5% developed less painful crisis and had higher percentage of reticulocytes. 结论。刚果SCA患者显示出低水平的HBF和F细胞，这会导致SCD的严重程度。SN -2090-1267 UR -https：//doi.org/10.1155/2012/105349 do -10.1155/2012/2012/105349 JF -Anemia PB -Hindawi Publishing Corporation KW- ER- ER- ER-