TY - JOUR A2 - 塞韦拉,里卡德AU - Banhuk,费尔南达•韦扬德AU - Pahim,布鲁纳·科雷亚AU - 豪尔赫,亚历桑德罗AU - Menolli,拉斐尔安德拉德PY - 2018 DA - 2018年9月30日TI - 对提取核抗体之间的关系抗原,抗核抗体,和自身免疫性疾病在巴西的公共医院SP - 9856910 VL - 2018 AB - 自身免疫性疾病(ADS)的一个特征是产生自身抗体为可提取性核自身抗原,其可以在不同类型的的鉴别帮助自身免疫性疾病和涉及不同抗核抗体(ANA)图案。本研究证实在公立医院提取的核抗原(ENA)抗体检测患者样本的轮廓,并与相关ANA模式和患者的诊断结果ENA。该研究综述了谁在巴拉那州西部一所公立医院接受抗ENA测试从2011年2月至2017年一月病人的医疗记录数据患者根据年龄,种族,性别,抗ENA测试分类结果,ANA的结果,和AD的存在或不存在。的172抗ENA测试的三十六个(20.9%)的样品为阳性,七(4.1%)的样品未确定,和129(75%)表现出阴性结果。的ANA试剂在抗ENA阳性样品的84.3%找到。抗SSA / RO自身抗体所表现出的组中的频率最高,为41.7%(15/36)。最常见的模式是洒满核细,这是在样本的24.3%中发现。 The association results indicated a significant relationship between ANA titer and diagnosis in the anti-ENA- and ANA-positive patients. The anti-ENA-negative patients were diagnosed with an AD in 35% (45/129) of the cases, and 75% (27/36) of the anti-ENA-positive patients were diagnosed with an AD. Systemic lupus erythematosus and scleroderma were the most common pathologies in the antigen-positive patients. The anti-ENA test is a good marker to aid in the complex clinical diagnosis of patients with autoimmune diseases. SN - 2090-0422 UR - https://doi.org/10.1155/2018/9856910 DO - 10.1155/2018/9856910 JF - Autoimmune Diseases PB - Hindawi KW - ER -