TY - JOUR A2 - Peña, Estefanía AU - Gao，佳子AU - Liu, Bei AU - Zhang, Min AU - Gong, He AU - Gao，Bingzhao PY - 2019 DA - 2019/12/01 TI -应变分布评价大鼠胫骨轴向压缩载荷下结合应变仪测量和有限元分析SP - 1736763六世- 2019 AB -本研究的目的是提供一种有效的方法来确定strain-load和量化中的应变分布的关系the whole tibia under axial compressive load on rats. Rat tibial models with axial compressive load were designed. Strains in three directions (0°, 45°, and 90°) at the proximal shaft of the tibia were measured by using a strain gauge rosette, which was used to calculate the maximum and minimum principal strains. Moreover, the strain at the midshaft of the tibia was measured by a single-element strain gauge. The slopes of the strain-load curves with different peak loads were calculated to assess the stability of the strain gauge measurement. Mechanical environment in the whole tibia by the axial compressive load was quantified using finite element analysis (FEA) based on microcomputed tomography images. The von Mises elastic strain distributions of the whole tibiae were evaluated. Slopes of the strain-load curves showed no significant differences among different peak loads (ANOVA; P > 0．05 )，说明由应变片测量得到的应变-载荷关系合理、稳定。有限元分析结果与实验结果吻合，误差小于15%(配对学生) t 以及, P > 0．05 )，表明有限元分析能够合理地模拟实验。有限元分析结果显示，von Mises弹性应变在中间最低，沿外侧方向向两侧逐渐增加，在远端胫腓骨早闭下的后侧von Mises弹性应变最大。本研究采用的应变片测量和有限元分析方法可以为获得大鼠胫骨在轴向压缩载荷作用下的力学环境提供一种可行的方法，为进一步探讨骨在轴向压缩载荷作用下的力学响应提供参考。SN - 1176-2322 UR - https://doi.org/10.1155/2019/1736763 DO - 10.1155/2019/1736763 JF -应用仿生和生物力学PB - Hindawi KW - ER -